2022 Mercedes-Benz E-Class

The volume E 350 4MATIC uses the 2.0L turbo I4 with 48V EQ Boost; for 2022 the range tops out at the 429-hp AMG E 53 because the V8 AMG E 63 S sedan skipped the model year in the US.

Peak torque from the 2.0L turbo arrives low and holds across a broad plateau.

Manufacturer 0–60 figure for the volume E 350; competitive for a four-cylinder mid-size luxury sedan.

The EQ Boost 48V integrated starter-generator smooths stop-start and fills low-end response, but the four-cylinder sounds and feels ordinary for the price next to the silky E 450 inline-six.

The 9G-TRONIC 9-speed automatic shifts smoothly and unobtrusively in Comfort mode; occasional hesitation on abrupt kickdown keeps it just short of the top band.

4MATIC AWD is optional on the E 350 and standard on the E 450 and AMG E 53 (4MATIC+ variable torque split); without the E 63 S for 2022 there is no drift-mode flagship, but AWD is available on every trim.

Three gas powertrains (2.0L I4 and 3.0L I6 mild hybrids, AMG 53 I6) cover mainstream to sporty buyers, but the V8 E 63 S was absent for 2022 and no plug-in hybrid, diesel or EV E-Class sedan was sold in the US.

EPA combined figure for the volume E 350 4MATIC with the 2.0L turbo I4 and 9-speed automatic.

EPA city figure for the volume E 350 4MATIC.

EPA highway figure for the volume E 350 4MATIC.

Computed from the EPA combined rating and the 17.4-gallon (66 L) fuel tank of the US-spec W213 sedan.

EPA's current annual fuel cost estimate for the volume trim on required premium fuel.

Premium unleaded is required on every 2022 E-Class sedan powertrain, a persistent running-cost penalty versus regular-fuel rivals; no diesel or US plug-in option.

NHTSA rated both the RWD and 4MATIC 2022 E-Class sedans five stars overall, with five stars in every sub-rating.

The 2022 E-Class sedan earned an IIHS Top Safety Pick+ with Good ratings across the small overlap (both sides), moderate overlap, side, roof and head restraint tests. The award applies only to cars with the optional front crash prevention, which holds it just below the top of the band.

On the volume E 350, AEB (Active Brake Assist) and Blind Spot Assist are standard. Adaptive cruise, lane keeping/centering and even lane departure warning are only in the optional Driver Assistance Package, which is thin for a luxury sedan at this price.

Vehicle-to-vehicle AEB rates Superior with both the standard and optional systems. Pedestrian detection is only Basic with the standard system by day and by night, and reaches Superior (day) only with the optional package.

Blind Spot Assist with Exit Warning (safe-exit alert) is standard. Active Blind Spot Assist with braking intervention and rear automatic braking / cross-traffic functions are optional.

Once optioned, Active Steering Assist centers smoothly and reviewers rated it among the better systems of its era. On the volume trim even lane departure warning is optional, which keeps it out of the top band.

DISTRONIC with stop-and-go, route-based speed adaptation and Active Lane Change Assist is a refined full-speed-range highway assist. It is optional rather than standard on the E 350.

No hands-free driving mode is offered. Active Steering Assist requires hands on the wheel, and Mercedes' DRIVE PILOT Level 3 system was never offered on the W213 E-Class.

The curve-adaptive LED projector headlights rate Good, but the standard LED reflector units on other trims rate only Acceptable. High-beam assist is standard with both.

Sightlines are typical of a mid-size sedan: good forward visibility, with thickish rear pillars and a high trunk deck. A surround-view camera is available in the parking packages.

IIHS rates the E-Class sedan's LATCH hardware Good for ease of use. The rear seat takes two car seats comfortably, but three across is tight.

Every 2022 E-Class sedan seats five.

The published figure includes the standard tilt/slide sunroof, which costs some headroom; it is about average for the class.

Adequate front legroom for a mid-size luxury sedan.

Generous rear headroom for the class; sources disagree slightly (37.6–38.2 in) depending on roof equipment.

Rear legroom in the W213 sedan is only adequate, and trails the Genesis G80 and BMW 5 Series.

The trunk is below the class average, though the split-folding rear seat helps with long items.

The center-console bin, covered cupholders and door pockets are competitive but not innovative, and wireless charging is optional.

The front seats are supportive and widely adjustable, with memory as standard and ventilated multicontour massage seats optional. The rear bench suits two adults on long trips.

The steel suspension with selective damping is supple and well controlled, and the optional Air Body Control is plusher still. Ride quality is a core E-Class strength.

A hushed, well-insulated cabin at highway speed; the E 350's four-cylinder becomes audible only under hard acceleration.

Heated memory front seats and dual-zone automatic climate are standard. The heated wheel and armrests ($1,050 Warmth & Comfort Package), ventilated seats and heated rear seats all cost extra on the E 350.

MY2022 is a W213 carry-over year after the 2021 refresh; the rear-drive E 350 sedan opens the range at $54,950 before destination, just above the sedan band's $55K ceiling.

The E 350 4MATIC is the volume seller, listing at $58,500 with destination, and is typically delivered with the Premium package plus several options, landing in the low-to-mid $60Ks.

Mercedes includes no scheduled maintenance for 2022, so dealer Service A/B visits plus repair exposure after the 4-yr/50k warranty put the E-Class near the top of the sedan band. Published projections vary widely; a mid-range figure consistent with adjacent E-Class years is used.

KBB records the 2022 E-Class down 36% after 3 years; extending the luxury-sedan curve through years 4–5 lands near half the MSRP retained, matching CarEdge's 47%-after-5-years E 350 figure.

Mercedes-Benz New Vehicle Limited Warranty is 4 years / 50,000 miles — level with BMW and Audi, behind Genesis's 5-yr/60k.

Powertrain coverage ends with the basic warranty at 4 years / 50,000 miles, below the 5-year band floor.

No included scheduled maintenance for 2022 (prepaid plans are extra-cost); owners get 24-hour Roadside Assistance for the warranty term and a Mercedes me connect trial — basic roadside only, behind rivals with included service.

$63,500 volume-trim price minus its estimated resale value after 5 years (48% retained, or about $30,480) leaves about $33,020 in depreciation. Add the projected $8,000 in 5-year maintenance and repairs, and owning this vehicle for 5 years costs about $41,020 in total.

2022 is the second year of the facelifted W213 (generation launched for 2017, refreshed for 2021) and a carry-over year, so most early-generation issues were sorted; predicted-reliability ratings sit around average for the class, with owner reports still citing electrical/MBUX glitches and occasional rattles.

Mercedes-Benz sits in the lower half of J.D. Power VDS and Consumer Reports brand rankings in this period — not bottom-tier like Alfa Romeo or Land Rover, but well behind Lexus, Toyota and Genesis and marginally behind BMW.

The volume E 350 is covered by two large multi-model fuel-pump campaigns carrying loss-of-drive-power risk plus a DISTRONIC hands-off-detection software fix; the fire-risk wiring/48V ground and battery-mount campaigns apply only to the six-cylinder E 450 and AMG E 53. Typical Mercedes activity, but the stalling risk is safety-relevant.

The volume E 350 uses the M264 2.0L turbo I4 (255 hp) with 48V EQ Boost starter-generator and the long-running 9G-Tronic 9-speed — both mature by 2022 with no systemic failure pattern. The fuel-pump recalls trace to a supplier component rather than engine design; the 48V hardware adds some long-term complexity.

The facelifted W213 cabin pairs the twin 12.3-inch widescreen MBUX display with open-pore wood, quality upholstery and 64-color ambient lighting; reviewers rank it among the richest cabins in the segment.

Mid-to-late-cycle W213 production is well sorted, with tight panel gaps and a quiet cabin; scattered owner reports of rattles and trim squeaks keep it short of the very top.

Roughly 380 Mercedes-Benz dealers across the US — denser than BMW or Audi, covering all major metros and most secondary markets. Service satisfaction is mid-pack among luxury brands.

Mercedes parts and labor are among the most expensive in the industry, but the W213 is a high-volume, long-running generation with a well-developed aftermarket and independent-shop familiarity.

The facelifted W213 carries a standard twin-12.3-inch widescreen cockpit.

MBUX is quick, with sharp graphics and natural voice control. The touchpad and finicky capacitive steering-wheel swipe controls drew criticism.

Apple CarPlay and Android Auto are standard but wired-only (USB-C) on the 2022 W213 sedan; wireless projection arrived with the 2024 W214.

The 'Hey Mercedes' natural-language assistant is among the best in the segment. Native navigation is good, with augmented-reality guidance available.

The standard FrontBass system is solid, and an excellent Burmester surround system (13 speakers, 590 W) is available.

A configurable 12.3-inch digital cluster with several display styles is standard.

MBUX receives over-the-air map and infotainment updates, but not the feature-adding whole-vehicle OTA of later MB.OS cars.

The Mercedes me app offers remote lock, locate and remote start/climate, but some services need a subscription after the trial.

USB-C ports are standard up front. Wireless charging is optional rather than standard, and there is no AC outlet. For 2022 the rear USB-C addition went to the Coupe/Cabriolet, not the sedan.

Push-button start is standard. KEYLESS-GO proximity entry and HANDS-FREE ACCESS come in the Premium Package, and the app provides remote start.

A rear camera is standard. The 360-degree camera, parking sensors and Active Parking Assist come in the Parking Assistance Package.

A color head-up display is an extra-cost option on the E 350, not standard.

The IIHS rates the LATCH Good and the rear doors open wide, but a 13.1 cu ft trunk and 36.2 in of rear legroom make strollers and rear-facing seats a squeeze.

An IIHS TOP SAFETY PICK+ with standard AEB, Blind Spot Assist and (new for 2022) automatic high beams. The award needs the optional front crash prevention, and the full DISTRONIC suite and the Good-rated projector headlights are extra-cost.

Excellent ride and seats for four. Heated rear seats and rear climate are optional, and the trunk limits a family's luggage.

Smooth 48V EQ Boost stop-start, a supple ride and optional Active Stop-and-Go make it a relaxing commuter.

24 MPG combined on premium fuel (E 350 4MATIC; 26 MPG RWD) is average to below average for a luxury four-cylinder.

A reasonable turning circle for the class, with the 360-degree camera and Active Parking Assist available; the sedan's length still needs care in tight garages.

Mercedes-Benz USA publishes no US tow rating for the E-Class sedan, and the trunk is modest; this is not a work vehicle.

The luxury-oriented cabin and complex electronics suit it poorly to hard use, despite a solid chassis.

No onboard AC power, no factory tow hitch and few work provisions.

Superb highway comfort and quiet, roughly 418 miles of range, and a strong optional DISTRONIC suite make it an excellent mile-eater.

Optional 4MATIC AWD handles snow and gravel roads, but low ground clearance and no tow rating keep the sedan pavement-bound; the All-Terrain wagon is the adventure variant.

The 40/20/40 split-folding rear seat gives pass-through flexibility, but the trunk is small and there are no roof rails or hitch.

Secure, well-controlled handling biased toward comfort; the BMW 5 Series is more agile.

Accurate and well weighted, but light on feedback.

Strong, progressive brakes with a firm, natural pedal and competitive stopping distances.

The 48V EQ Boost starter-generator makes stop-start seamless and fills turbo lag. The 9G-TRONIC is smooth, with some hesitation on abrupt kickdowns.

Well isolated at cruise, but the 2.0L four sounds ordinary and a little gruff under load next to the E 450's inline-six.

An average circle for a mid-size sedan; 4MATIC is slightly wider than RWD.

Wide seat and wheel adjustment, standard memory seats and good forward sightlines. The capacitive wheel controls and touchpad are minor ergonomic missteps.

Pleasant and polished but comfort-focused; the E 350 lacks the character of the E 450 or AMG E 53.

For 2022 the E 350 gains standard adaptive LED headlights with Adaptive Highbeam Assist, on top of dual 12.3-in MBUX displays, the 48V mild-hybrid turbo-four and automatic emergency braking; adaptive cruise and the full Driver Assistance suite remain costly options, typical of German luxury.

Priced in line with the BMW 5 Series and Audi A6 but above the Genesis G80 and Cadillac CT5 for similar content, and the E 350's 255-hp four is merely adequate for $56K+. Fair value, not a bargain.

The 2022 sedan spans E 350 RWD/4MATIC, E 450 4MATIC and AMG E 53 from $54,950 to $75,000, with wagon, coupe and cabriolet body styles alongside; the V8 AMG E 63 S sedan skipped 2022, leaving a gap at the top.

The E-Class remains one of the two best-selling midsize luxury sedans in the US alongside the 5 Series, but 2022 volume was constrained by chip shortages and a long-run shift to SUVs; it no longer appears among Mercedes' volume leaders (GLC, GLE, C-Class).

Mercedes-Benz is among the most aspirational luxury brands, and the E-Class is its core executive sedan with a long loyal following.

MY2022 sold through the 2021–2022 semiconductor-shortage market, when luxury inventory was thin and discounts largely disappeared; buyers saw modest lease support at best and often paid sticker.

MY2022 is the sixth year of the W213 generation but only the second after the substantial 2021 facelift (new MBUX, styling, mild-hybrid engines), so it is mid-cycle and current; the replacement W214 was still over a year away.

The refreshed E-Class was consistently praised for ride comfort, refinement, cabin quality and MBUX tech (KBB expert 4.7/5), a frequent runner-up to the BMW 5 Series and Genesis G80 in comparisons rather than the outright pick.